Geographic Variation In The Chemical Composition And Antioxidant Properties Of Phenolic Compounds From Algerian Propolis

Résumé: The main purpose of this research is to assess the antioxidant properties of methanolic extracts of propolis from the provinces of Tipaza (RT), Tebessa (RTb), El-Oued (RE), and Constantine (RC) in Algeria, and the values will be associated with total amounts of polyphenolic compounds. In this study, Spectrophotometry was used to calculate the total phenolic and flavonoid contents of a methanolic extract of propolis. Further, the antioxidant properties of the extracts were calculated using the reducing power (FRAP and RP) and radical scavenging (DPPH assays) and determined antioxidant total by (phosphomolybdate assay). As a result, the total polyphenolic content was 384.7± 18.0, 353.2±13.9, 105.17±2.77, and 42.12±1.42 mg gallic acid equivalent/g extract in methanolic extracts of propolis from RT, RTb, RC, and RE, respectively. RT, RTb, RC and RE propolis had IC50 values of 0.38488, 0.4340, 1.2807 and 0.8645 mg/mL, respectively, for scavenging DPPH radicals. Finally, our findings support the use of a natural source of antioxidant compounds that may be used in the prevention of free radical-related diseases. Also, our findings indicate that geographic origin matters, with sunshine hours and temperature being the most important determinants of Propolis phenolic accumulation and antioxidant properties. Tipaza propolis, on the other hand, had the highest antioxidant activity values.

Publié dans la revue: Applied Biology in Saharan Areas